Priligy (Dapoxetine) is the marketing name for dapoxetine drug, which is used in the treatment of premature ejaculation. The drug was created by Eli Lilly and originally intended as an antidepressant; however, soon it was found that dapoxetine is effective for PE treatment. In 2003, the formula was sold to Jonson & Jonson, and after necessary clinical trials were conducted, the drug was certified as a PE medication and gradually gained recognition in countries worldwide.
Dapoxetine is a selective serotonin reuptake inhibitor that suppresses mechanisms and reflexes underlying the ejaculation process. In contrast to other SSRI drugs, which must be taken daily for PE treatment, dapoxetine has two advantages: it can be taken occasionally due to its rapid action and it is quickly removed from the body, minimizing drug accumulation, side effects and risk of developing addiction.
The efficacy of dapoxetine was proved by trials that showed an 2x-3x increase in the duration of sexual intercourse, depending on the dosage.
Indeed, with the discovery of SSRI drugs and the beginning of pharmacological treatment of PE, there was a new stage in addressing this condition. In the past, the importance of treating this common disorder was generally ignored. At the present, more and more men decide to seek medical advice for PE, and it becomes obvious that premature ejaculation causes bother and distress.
When should you start PE treatment with Priligy or other dapoxetine drugs? Only a physician who will thoroughly examine your medical history can affirm that dapoxetine usage will be safe and relevant for your case. Beforehand, you can determine if you actually have PE according to some generally accepted criteria.
In medical literature, PE is broadly defined as “ejaculation that happens with minimal stimulation, before the man desires it, without having enough control over it, causing dissatisfaction, bother or distress in one or both partners.” According to widely accepted criteria, sexual intercourse that commonly lasts less than 1.5-2 minutes shows a high probability of PE. The condition can be both congenital or acquired. Currently, it is believed that the most common cause of the disease is insecurity and anxious personality.
An important prerequisite for starting a treatment is certainly a feeling of dissatisfaction in one or both partners due to a lack of prolonged sexual intercourse. Thus, treatment with dapoxetine is used in men who are not able to control ejaculation sufficiently and suffer from it directly or indirectly.
Priligy, Westoxetin, and other drugs that contain dapoxetine are prescribed for men 18-64 years old. The medication should not be taken by people who are hypersensitive to dapoxetine. Severe heart diseases, severe impairment of kidney or liver function, epilepsy and some other conditions may be contradictory to dapoxetine usage. Taking Priligy may be unsafe for some psychological disorders, such as mania or bipolar disorder. Please consider these contradictions and drug interactions before ordering dapoxetine.
Dapoxetine can be taken as a stand-alone medication, 1-3 hours before sexual intercourse.
The effectiveness of treatment increases if other drugs from the SSRI group, such as paroxetine, clomipramin, sertraline, and fluoxetine are taken on a daily basis. It should be noted that officially the four mentioned drugs are not approved for the treatment of PE; however, they are often prescribed for PE off-label.
Thus, it is common to take 30 mg of paroxetine daily and 60 mg of dapoxetine 1-2 hours before sex in order to achieve the best result, increasing the duration of sexual intercourse up to 9 times. Please note that only your physician should determine the exact dosage of these drugs.
It is believed that Priligy can be taken without any dietary restrictions. Eating fatty foods can slow down the time of onset very insignificantly. In clinical trials, it was shown that alcohol does not significantly affect the efficiency of dapoxetine either.
A physician should examine the medical history of the patient to ensure that PE is not caused by such conditions as urinary infection, etc. Inform your doctor if you suffer from depression or other psychological disorders, since taking dapoxetine may be risky in certain psychological conditions. Report any medications you took within the last 14 days.
Dapoxetine and other serotonin reuptake inhibitors should not be used with MAO inhibitors and other serotonergic drugs, thioridazine, active inhibitors of CYP3A4 and a number of other drugs. After using the above drugs, it should be two weeks before starting dapoxetine. Accordingly, you need to wait 7 days after taking dapoxetine before you start these medications.
The joint administration of dapoxetine, tadalafil (erectile dysfunction drug knows as Cialis) and sildenafil (Viagra) was examined during clinical trials. As a result, it was found that tadalafil does not interact with dapoxetine, however, sildenafil enhances the effect of dapoxetine by 20%.
Before using dapoxetine with other medications, it is extremely important to consult a doctor.
The frequency and intensity of side effects is directly dependent on the dosage of drug. Doses of 30 or 60 mg are considered safe and efficient. In general, Priligy rarely gives side effects. The most common are nausea, headache, diarrhea, and drowsiness. During the trial, about 10% and 20% of participants reported nausea for 30mg and 60mg accordingly. However, it was later discovered that men who continued to take 60 mg for a longer time mostly reported that nausea has disappeared, and only 2% were still experiencing this adverse reaction. In rare cases, participants reported a libido decrease caused by dapoxetine. Among psychological adverse effects, some said to experience apathy, anxiety and agitation.
Taking dapoxetine occasionally will not cause an addiction. However, daily use of SSRI for PE treatment can cause mild withdrawal symptoms like anxiety and irritancy after discontinuing the drug.
To reduce the risk of side effects, take the minimal effective dosage of the drug. Studies have not identified ways to address such common reactions as nausea and headache. However, it should be noted that with prolonged use of dapoxetine, side effects may cease to occur without any additional measures.
You can order Priligy, Westoxetin and generic drugs that contain dapoxetine online. The drug is already approved and sold in European countries such as UK, Germany, Sweden, and Austria, as well as New Zealand. Although its efficiency and safety were proven by many studies since 2005, dapoxetine is still waiting for FDA approval. That said, by 2018 it is illegal to buy any dapoxetine drugs in the US. However, practically speaking, people who order Priligy for personal use are doubtfully to face any charges for importing dapoxetine.
1. How long does Priligy work?
After intake, the peak concentration of the drug is achieved within 1.5-2 hours. Since dapoxetine is rapidly removed from the body, it is desirable to take Priligy no more than 3 hours before sexual intercourse.
2. Which dosage should I take?
Only a physician can determine the optimal dosage of medication correctly. Studies have shown that dosages of 30 mg and 60 mg are effective, safe and rarely cause side effects.
3. How effective is Priligy?
Priligy and other dapoxetine-containing drugs can help you last 3-5 times longer than usual.
4. Is Priligy safe to use?
Currently, dapoxetine is in the final stages of FDA approval which includes human clinical trials with larger groups of participants (300-3000). The drug has already passed two stages of safety and efficiency assessment and also has been approved in many European countries.
5. Are there generic versions of Priligy?
Although Priligy is very effective, the branded pills are also quite expensive. You can buy other dapoxetine-containing drugs that cost less and give you the same result. Amazingly, generic versions of Priligy cost approx. 10 times less than their branded counterparts.
Premature ejaculation is one of the most common sexual disorders observed in 20-40% of men. Although it was not given proper attention before, now it is obvious that PE can have a very negative impact on self-esteem and the relationship between partners. However, currently there are products such as Priligy to deal with this problem in a safe and effortless way. Consult your doctor to discover if you can take Priligy as your long-term PE treatment.